Rb deficiency, neuronal survival and neurodegeneration: In search of the perfect mouse model
Three decades following the introduction of the first Rb knockout (KO) mouse model, the role of this critical protein in regulating brain development during embryogenesis and beyond remains a major scientific interest. Rb is a tumor suppressor gene known as the master regulator of the G1/S checkpoin...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-01-01
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| Series: | Current Research in Neurobiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665945X23000025 |