A multifunctional nanogel encapsulating layered double hydroxide for enhanced osteoarthritis treatment via protection of chondrocytes and ECM

A multifunctional nanogel encapsulating layered double hydroxide for enhanced osteoarthritis treatment via protection of chondrocytes and ECM

Osteoarthritis (OA) is characterized by progressive and irreversible damage to the articular cartilage and a consecutive inflammatory response. However, the majority of clinical drugs for OA treatment only alleviate symptoms without addressing the fundamental pathology. To mitigate this issue, we de...

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Bibliographic Details
Main Authors: Changxing Liu, Yawei Sun, Dengju Li, Fan Wang, Haojue Wang, Senbo An, Shui Sun
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Materials Today Bio
Subjects:
Osteoarthritis
Extracellular matrix
Chondrocytes
Layered double hydroxide (LDH)
Strontium (Sr2+)
Tannic acid
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424000930

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http://www.sciencedirect.com/science/article/pii/S2590006424000930

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