Alpha-Synuclein Contribution to Neuronal and Glial Damage in Parkinson’s Disease

Alpha-Synuclein Contribution to Neuronal and Glial Damage in Parkinson’s Disease

Parkinson’s disease (PD) is a complex neurodegenerative disease characterized by the progressive loss of dopaminergic neurons in the substantia nigra and the widespread accumulation of alpha-synuclein (αSyn) protein aggregates. αSyn aggregation disrupts critical cellular processes, including synapti...

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Bibliographic Details
Main Authors: Kamil Saramowicz, Natalia Siwecka, Grzegorz Galita, Aleksandra Kucharska-Lusina, Wioletta Rozpędek-Kamińska, Ireneusz Majsterek
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:International Journal of Molecular Sciences
Subjects:
Parkinson’s disease
α-synuclein
neurodegeneration
Lewy bodies
aggregation
neurons
Online Access:https://www.mdpi.com/1422-0067/25/1/360

Internet

https://www.mdpi.com/1422-0067/25/1/360

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