A multiwell plate-based system for toxicity screening under multiple static or cycling oxygen environments

Abstract Tumor tissue contains a continuous distribution of static and dynamically changing oxygen environments with levels ranging from physiologically normal oxygen down to anoxia. However, in vitro studies are often performed under oxygen levels that are far higher than those found in vivo. A num...

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Bibliographic Details
Main Authors: Ming Yao, Glenn Walker, Michael P. Gamcsik
Format: Article
Language:English
Published: Nature Portfolio 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-83579-1