Intron retention enhances gene regulatory complexity in vertebrates

Intron retention enhances gene regulatory complexity in vertebrates

Abstract Background While intron retention (IR) is now widely accepted as an important mechanism of mammalian gene expression control, it remains the least studied form of alternative splicing. To delineate conserved features of IR, we performed an exhaustive phylogenetic analysis in a highly purifi...

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Bibliographic Details
Main Authors: Ulf Schmitz, Natalia Pinello, Fangzhi Jia, Sultan Alasmari, William Ritchie, Maria-Cristina Keightley, Shaniko Shini, Graham J. Lieschke, Justin J-L Wong, John E. J. Rasko
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Genome Biology
Subjects:
Transcriptomic complexity
Granulocytes
Evolution
Alternative splicing
Intron retention
Gene regulation
Online Access:http://link.springer.com/article/10.1186/s13059-017-1339-3

Internet

http://link.springer.com/article/10.1186/s13059-017-1339-3

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