The microbiota restrains neurodegenerative microglia in a model of amyotrophic lateral sclerosis
Abstract Background The gut microbiota can affect neurologic disease by shaping microglia, the primary immune cell in the central nervous system (CNS). While antibiotics improve models of Alzheimer’s disease, Parkinson’s disease, multiple sclerosis, and the C9orf72 model of amyotrophic lateral scler...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-03-01
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Series: | Microbiome |
Online Access: | https://doi.org/10.1186/s40168-022-01232-z |