Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody
Regulatory T cells (T<sub>regs</sub>) are major drivers behind immunosuppressive mechanisms and present a major hurdle for cancer therapy. T<sub>regs</sub> are characterized by a high expression of CD25, which is a potentially valuable target for T<sub>reg</sub> d...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-08-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/15/8707 |