Temperature sensitive influenza A virus genome replication results from low thermal stability of polymerase-cRNA complexes
<p>Abstract</p> <p>Background</p> <p>The RNA-dependent RNA polymerase of Influenza A virus is a determinant of viral pathogenicity and host range that is responsible for transcribing and replicating the negative sense segmented viral genome (vRNA). Transcription produce...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-08-01
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Series: | Virology Journal |
Online Access: | http://www.virologyj.com/content/3/1/58 |