Protein phosphatase 4 promotes chromosome pairing and synapsis, and contributes to maintaining crossover competence with increasing age.

Prior to the meiotic divisions, dynamic chromosome reorganizations including pairing, synapsis, and recombination of maternal and paternal chromosome pairs must occur in a highly regulated fashion during meiotic prophase. How chromosomes identify each other's homology and exclusively pair and s...

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Main Authors: Aya Sato-Carlton, Xuan Li, Oliver Crawley, Sarah Testori, Enrique Martinez-Perez, Asako Sugimoto, Peter M Carlton
פורמט: Article
שפה:English
יצא לאור: Public Library of Science (PLoS) 2014-10-01
סדרה:PLoS Genetics
גישה מקוונת:http://europepmc.org/articles/PMC4207613?pdf=render