Thioredoxin-1 attenuates early graft loss after intraportal islet transplantation in mice.

Thioredoxin-1 attenuates early graft loss after intraportal islet transplantation in mice.

AIMS: Recent studies suggest that decreasing oxidative stress is crucial to achieve successful islet transplantation. Thioredoxin-1 (TRX), which is a multifunctional redox-active protein, has been reported to suppress oxidative stress. Furthermore, it also has anti-inflammatory and anti-apoptotic ef...

Full description

Bibliographic Details
Main Authors: Kengo Asami, Akiko Inagaki, Takehiro Imura, Satoshi Sekiguchi, Keisei Fujimori, Hiroshi Masutani, Junji Yodoi, Susumu Satomi, Noriaki Ohuchi, Masafumi Goto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3739792?pdf=render

Internet

http://europepmc.org/articles/PMC3739792?pdf=render

Similar Items