Selective sigma-2 ligands preferentially bind to pancreatic adenocarcinomas: applications in diagnostic imaging and therapy

<p>Abstract</p> <p>Background</p> <p>Resistance to modern adjuvant treatment is in part due to the failure of programmed cell death. Therefore the molecules that execute the apoptotic program are potential targets for the development of anti-cancer therapeutics. The sig...

Full description

Bibliographic Details
Main Authors: Johnston Fabian, Chang Katherine, Jones Lynne, Xu Jinbin, Goedegebuure Peter S, Simon Peter O, McDunn Jonathan E, Kashiwagi Hiroyuki, Trinkaus Kathryn, Hotchkiss Richard S, Mach Robert H, Hawkins William G
Format: Article
Language:English
Published: BMC 2007-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/6/1/48