Heightened Expression of Cyclooxygenase-2 and Peroxisome Proliferator-Activated Receptor-δ in Human Endometrial Adenocarcinoma

Heightened Expression of Cyclooxygenase-2 and Peroxisome Proliferator-Activated Receptor-δ in Human Endometrial Adenocarcinoma

Epidemiological studies indicate that nonsteroidal anti-inflammatory drugs (NSAIDs) significantly reduce the risk and mortality from colorectal cancer, in part by inhibiting prostaglandin (PG) synthesis. Cyclooxygenase (COX), the rate-limiting enzyme in PG biosynthesis, exists in two isoforms, COX-1...

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Bibliographic Details
Main Authors: Beverly J. Tong, Jian Tan, Lovella Tajeda, Sanjoy K. Das, Julia A. Chapman, Raymond N. DuBois, Sudhansu K. Dey
Format: Article
Language:English
Published: Elsevier 2000-01-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
cyclooxygenase
endometrial cancer
prostaglandins
human
uterus
Online Access:http://www.sciencedirect.com/science/article/pii/S147655860080038X

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http://www.sciencedirect.com/science/article/pii/S147655860080038X

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