Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism.

Direct Renin Inhibition with Aliskiren Improves Ischemia-Induced Neovasculogenesis in Diabetic Animals via the SDF-1 Related Mechanism.

Aliskiren is a direct renin inhibitor which is suggested to modify proangiogenic cells in addition to lower blood pressure. Given that angiogenesis is impaired in the presence of diabetes mellitus, we would like to investigate whether and how aliskiren enhances endothelial progenitor cells (EPCs) an...

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Bibliographic Details
Main Authors: Ting-Ting Chang, Tao-Cheng Wu, Po-Hsun Huang, Chih-Pei Lin, Jia-Shiong Chen, Liang-Yu Lin, Shing-Jong Lin, Jaw-Wen Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4549314?pdf=render

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http://europepmc.org/articles/PMC4549314?pdf=render

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