Common gene signatures and molecular mechanisms of diabetic nephropathy and metabolic syndrome

BackgroundDiabetic nephropathy (DN) is the leading cause of end-stage renal disease. Multiple metabolic toxicities, redox stress, and endothelial dysfunction contribute to the development of diabetic glomerulosclerosis and DN. Metabolic syndrome (MetS) is a pathological state in which the body’s abi...

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Bibliographic Details
Main Authors: Chengyu Zhang, Han Li, Shixiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Public Health
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2023.1150122/full