The contribution of PFAS to thyroid hormone-displacing activity in Dutch waters: A comparison between two in vitro bioassays with chemical analysis

The contribution of PFAS to thyroid hormone-displacing activity in Dutch waters: A comparison between two in vitro bioassays with chemical analysis

Per- and polyfluoroalkyl substances (PFAS) are a group of xenobiotics that are widely distributed throughout the aquatic environment. Many PFAS are possible thyroid hormone (TH) system disrupting compounds, because they have the capacity to -amongst other- inhibit the TH thyroxine (T4) from binding...

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Bibliographic Details
Main Authors: J.K.H. de Schepper, Y. van Oorschot, R.J. Jaspers, T. Hamers, M.H. Lamoree, P. Behnisch, H. Besselink, C.J. Houtman
Format: Article
Language:English
Published: Elsevier 2023-11-01
Series:Environment International
Subjects:
In vitro
Bioassay
Transthyretin
Endocrine disruption
Xenobiotics
Drinking water
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412023005299

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http://www.sciencedirect.com/science/article/pii/S0160412023005299

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