High-flow nasal cannula therapy with sequential noninvasive ventilation versus noninvasive ventilation alone as the initial ventilatory strategy in acute COPD exacerbations: study protocol for a randomized controlled trial

Abstract Background Noninvasive ventilation (NIV) is the recommended mode of ventilation used in acute respiratory failure secondary to an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Recent data has shown that high-flow nasal cannula (HFNC) treatment can be an alternative f...

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Bibliographic Details
Main Authors: Shuai Liu, Joseph Harold Walline, Huadong Zhu, Yan Li, Chunting Wang, Jihai Liu
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-022-06963-w