Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease

Beneficial effects of rolipram in the R6/2 mouse model of Huntington's disease

We have previously showed that rolipram, a phosphodiesterase type IV inhibitor, displays a neuroprotective effect in a rat quinolinic acid model of HD [DeMarch Z., Giampa C., Patassini S., Martorana A., Bernardi G. and Fusco F.R., (2007) Beneficial effects of rolipram in a quinolinic acid model of s...

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Bibliographic Details
Main Authors: Zena DeMarch, Carmela Giampà, Stefano Patassini, Giorgio Bernardi, Francesca Romana Fusco
Format: Article
Language:English
Published: Elsevier 2008-06-01
Series:Neurobiology of Disease
Subjects:
Phosphodiesterase inhibitors
CREB
Huntington's disease
Transgenic mouse
Confocal microscopy
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996108000405

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http://www.sciencedirect.com/science/article/pii/S0969996108000405

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