FIP200 restricts RNA virus infection by facilitating RIG-I activation

Lingyan Wang et al. report that the autophagy-associated protein FIP200 interacts with the RNA sensor RIG-I to trigger activation of the type I interferon pathway.

Bibliographic Details
Main Authors: Lingyan Wang, Kun Song, Wenzhuo Hao, Yakun Wu, Girish Patil, Fang Hua, Yiwen Sun, Chaoqun Huang, Jerry Ritchey, Clinton Jones, Lin Liu, Jun-Lin Guan, Shitao Li
Format: Article
Language:English
Published: Nature Portfolio 2021-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-021-02450-1