FIP200 restricts RNA virus infection by facilitating RIG-I activation
Lingyan Wang et al. report that the autophagy-associated protein FIP200 interacts with the RNA sensor RIG-I to trigger activation of the type I interferon pathway.
Main Authors: | Lingyan Wang, Kun Song, Wenzhuo Hao, Yakun Wu, Girish Patil, Fang Hua, Yiwen Sun, Chaoqun Huang, Jerry Ritchey, Clinton Jones, Lin Liu, Jun-Lin Guan, Shitao Li |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-07-01
|
Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-021-02450-1 |
Similar Items
-
FKBP5 Regulates RIG-I-Mediated NF-κB Activation and Influenza A Virus Infection
by: Wenzhuo Hao, et al.
Published: (2020-06-01) -
Regulation of immune checkpoint blockade efficacy in breast cancer by FIP200: A canonical-autophagy-independent function
by: Syn Kok Yeo, et al.
Published: (2020-07-01) -
ZBTB28 induces autophagy by regulation of FIP200 and Bcl-XL facilitating cervical cancer cell apoptosis
by: Li Li, et al.
Published: (2021-04-01) -
FIP200 is Involved in Murine Pseudomonas Infection by Regulating HMGB1 Intracellular Translocation
by: Yi Li, et al.
Published: (2014-05-01) -
Comparative influenza protein interactomes identify the role of plakophilin 2 in virus restriction
by: Lingyan Wang, et al.
Published: (2017-02-01)