Coordination of KSHV latent and lytic gene control by CTCF-cohesin mediated chromosome conformation.

Herpesvirus persistence requires a dynamic balance between latent and lytic cycle gene expression, but how this balance is maintained remains enigmatic. We have previously shown that the Kaposi's Sarcoma-Associated Herpesvirus (KSHV) major latency transcripts encoding LANA, vCyclin, vFLIP, v-mi...

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Bibliographic Details
Main Authors: Hyojeung Kang, Andreas Wiedmer, Yan Yuan, Erle Robertson, Paul M Lieberman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-08-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3158054?pdf=render