Involvement of Antioxidant and Prevention of Mitochondrial Dysfunction, Anti-Neuroinflammatory Effect and Anti-Apoptotic Effect: Betaine Ameliorates Haloperidol-Induced Orofacial Dyskinesia in Rats

With its pathophysiological characteristics strongly similar to patients with tardive dyskinesia (TD), haloperidol (HP)-induced neurotoxicity and orofacial dyskinesia (OD) in animal models have long been used to study human TD. This study aimed to explore the potential protective effects of betaine...

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Bibliographic Details
Main Authors: Hsiang-Chien Tseng, Mao-Hsien Wang, Chih-Hsiang Fang, Yi-Wen Lin, Hung-Sheng Soung
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/13/7/1064