OVOL2 sustains postnatal thymic epithelial cell identity

OVOL2 sustains postnatal thymic epithelial cell identity

Abstract Distinct pathways and molecules may support embryonic versus postnatal thymic epithelial cell (TEC) development and maintenance. Here, we identify a mechanism by which TEC numbers and function are maintained postnatally. A viable missense allele (C120Y) of Ovol2, expressed ubiquitously or s...

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Bibliographic Details
Main Authors: Xue Zhong, Nagesh Peddada, Jianhui Wang, James J. Moresco, Xiaowei Zhan, John M. Shelton, Jeffrey A. SoRelle, Katie Keller, Danielle Renee Lazaro, Eva Marie Y. Moresco, Jin Huk Choi, Bruce Beutler
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43456-z

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https://doi.org/10.1038/s41467-023-43456-z

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