The prepared and characterized polysaccharide polymer in Saposhnikovia divaricata(Trucz.) Schischk effectively controls the course of rheumatoid arthritis via TLR4/TRAF6–NF-κB/IκB-α signaling pathway

The prepared and characterized polysaccharide polymer in Saposhnikovia divaricata(Trucz.) Schischk effectively controls the course of rheumatoid arthritis via TLR4/TRAF6–NF-κB/IκB-α signaling pathway

Saposhnikovia divaricata (Trucz.) Schischk is a traditional Chinese herbal medicine that is widely used to regulate rheumatoid arthritis (RA). We extracted SD-a, a polysaccharide from S. divaricata, and analyzed its structure by chemical and spectral analysis. We further studied the anti-rheumatoid...

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Bibliographic Details
Main Authors: Xialin Sun, Tingwen Zhang, Shuangli Liu, Yan Zhao, Xin Sun
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Saposhnikovia divaricata polysaccharide
Structural characterization
Rheumatoid arthritis
Invasion
TLR4–NF-κB pathway
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223002044

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http://www.sciencedirect.com/science/article/pii/S0753332223002044

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