Metabolic profiling reveals new serum signatures to discriminate lupus nephritis from systemic lupus erythematosus

Metabolic profiling reveals new serum signatures to discriminate lupus nephritis from systemic lupus erythematosus

BackgroundLupus nephritis (LN) occurs in 50% of patients with systemic lupus erythematosus (SLE), causing considerable morbidity and even mortality. Previous studies had shown the potential of metabolic profiling in the diagnosis of SLE or LN. However, few metabonomics studies have attempted to dist...

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Bibliographic Details
Main Authors: Yamei Zhang, Lingling Gan, Jie Tang, Dan Liu, Gang Chen, Bei Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
systemic lupus erythematosus
lupus nephritis
non-targeted metabonomics
high performance liquid chromatography tandem mass spectrometry
serum signatures
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.967371/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.967371/full

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