Impaired Testicular Function without Altering Testosterone Concentration Using an Anti-Follicular-Stimulating Hormone Receptor (Anti-FSHr) Single-Chain Variable Fragment (scFv) in Long-Tailed Macaques (<i>Macaca fascicularis</i>)

Impaired Testicular Function without Altering Testosterone Concentration Using an Anti-Follicular-Stimulating Hormone Receptor (Anti-FSHr) Single-Chain Variable Fragment (scFv) in Long-Tailed Macaques (<i>Macaca fascicularis</i>)

FSHr antibodies have been shown to inhibit the differentiation of spermatogonia to primary spermatocytes, resulting in infertility without a pathological effect on reproductive organs. The aim of this study was to develop single-chain variable fragments (scFvs) against the follicular-stimulating hor...

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Bibliographic Details
Main Authors: Pakpoom Navanukraw, Sroisuda Chotimanukul, Taratorn Kemthong, Kiattawee Choowongkomon, Kaywalee Chatdarong
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Animals
Subjects:
contraceptive
monkey
nanobody
phage display
single-domain antibody
Online Access:https://www.mdpi.com/2076-2615/13/14/2282

Internet

https://www.mdpi.com/2076-2615/13/14/2282

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