Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway

Circular RNA ZBTB46 depletion alleviates the progression of Atherosclerosis by regulating the ubiquitination and degradation of hnRNPA2B1 via the AKT/mTOR pathway

Abstract Background CircZBTB46 has been identified as being associated with the risk of coronary artery disease (CAD) and has the potential to be a diagnostic biomarker for CAD. However, the specific function and detailed mechanism of circZBTB46 in CAD are still unknown. Methods The expression level...

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Bibliographic Details
Main Authors: Yahong Fu, Qiaowei Jia, Mengmeng Ren, Hengjie Bie, Xin Zhang, Qian Zhang, Shu He, Chengcheng Li, Hanxiao Zhou, Yanjun Wang, Xiongkang Gan, Zhengxian Tao, Xiumei Chen, Enzhi Jia
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Immunity & Ageing
Subjects:
Coronary artery Disease
Atherosclerotic plaque; circular RNA
RNA-binding protein
Online Access:https://doi.org/10.1186/s12979-023-00386-0

Internet

https://doi.org/10.1186/s12979-023-00386-0

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