Total Synthesis and Biological Evaluation of Modified Ilamycin Derivatives

Total Synthesis and Biological Evaluation of Modified Ilamycin Derivatives

Ilamycins/rufomycins are marine cycloheptapeptides containing unusual amino acids. Produced by <i>Streptomyces</i> sp., these compounds show potent activity against a range of mycobacteria, including multidrug-resistant strains of <i>Mycobacterium tuberculosis</i>. The cyclic...

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Bibliographic Details
Main Authors: Jennifer Greve, Axel Mogk, Uli Kazmaier
Format: Article
Language:English
Published: MDPI AG 2022-10-01
Series:Marine Drugs
Subjects:
ilamycins
tuberculosis
cyclopeptides
total synthesis
natural products
ClpC1
Online Access:https://www.mdpi.com/1660-3397/20/10/632

Internet

https://www.mdpi.com/1660-3397/20/10/632

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