E-Selectin-Dependent Inflammation and Lipolysis in Adipose Tissue Exacerbate Steatosis-to-NASH Progression via S100A8/9Summary

E-Selectin-Dependent Inflammation and Lipolysis in Adipose Tissue Exacerbate Steatosis-to-NASH Progression via S100A8/9Summary

Background & Aims: Nonalcoholic steatohepatitis (NASH) is a leading cause of chronic liver disease, characterized by steatosis and hallmark liver neutrophil infiltration. NASH also is associated with adipose tissue inflammation, but the role of adipose tissue inflammation in NASH pathogenesi...

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Bibliographic Details
Main Authors: Robim M. Rodrigues, Yong He, Seonghwan Hwang, Adeline Bertola, Bryan Mackowiak, Yeni Ait Ahmed, Wonhyo Seo, Jing Ma, Xiaolin Wang, Seol Hee Park, Yukun Guan, Yaojie Fu, Tamara Vanhaecke, Dechun Feng, Bin Gao
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Subjects:
Nonalcoholic Fatty Liver Disease (NAFLD)
Steatohepatitis
Neutrophils
Paquinimod
CXCL1
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X21001697

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http://www.sciencedirect.com/science/article/pii/S2352345X21001697

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