IFITM proteins restrict antibody-dependent enhancement of dengue virus infection.

Interferon-inducible transmembrane (IFITM) proteins restrict the entry processes of several pathogenic viruses, including the flaviviruses West Nile virus and dengue virus (DENV). DENV infects cells directly or via antibody-dependent enhancement (ADE) in Fc-receptor-bearing cells, a process thought...

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Bibliographic Details
Main Authors: Ying Kai Chan, I-Chueh Huang, Michael Farzan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3316688?pdf=render