Fimbriae reprogram host gene expression - Divergent effects of P and type 1 fimbriae.

Pathogens rely on a complex virulence gene repertoire to successfully attack their hosts. We were therefore surprised to find that a single fimbrial gene reconstitution can return the virulence-attenuated commensal strain Escherichia coli 83972 to virulence, defined by a disease phenotype in human h...

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Bibliographic Details
Main Authors: Ines Ambite, Daniel S C Butler, Christoph Stork, Jenny Grönberg-Hernández, Bela Köves, Jaroslaw Zdziarski, Jerome Pinkner, Scott J Hultgren, Ulrich Dobrindt, Björn Wullt, Catharina Svanborg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-06-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007671