Antioxidants prevent particulate matter-induced senescence of lung fibroblasts

Antioxidants prevent particulate matter-induced senescence of lung fibroblasts

Particulate matter (PM) contributes to human diseases, particularly lung disease; however, the molecular mechanism of its action is yet to be determined. Herein, we found that prolonged PM exposure induced the cellular senescence of normal lung fibroblasts via a DNA damage-mediated response. This PM...

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Bibliographic Details
Main Authors: Sein Jin, Sung-Jin Yoon, Na-Young Jung, Wang Sik Lee, Jinyoung Jeong, Young-Jun Park, Wantae Kim, Doo-Byoung Oh, Jinho Seo
Format: Article
Language:English
Published: Elsevier 2023-03-01
Series:Heliyon
Subjects:
Particulate matter
Cellular senescence
Reactive oxygen species
DNA damage Response
Antioxidants
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023013865

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023013865

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