The <it>14-3-3</it>σ gene promoter is methylated in both human melanocytes and melanoma

<p>Abstract</p> <p>Background</p> <p>Recent evidence demonstrates that 14-3-3σ acts as a tumor suppressor gene inactivated by methylation of its 5' CpG islands in epithelial tumor cells, while remaining un-methylated in normal human epithelia. The methylation analy...

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Bibliographic Details
Main Authors: Fodstad Oystein, Howell Paul, Ren Suping, Liu Suhu, Riker Adam I
Format: Article
Language:English
Published: BMC 2009-05-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/162