The <it>14-3-3</it>σ gene promoter is methylated in both human melanocytes and melanoma
<p>Abstract</p> <p>Background</p> <p>Recent evidence demonstrates that 14-3-3σ acts as a tumor suppressor gene inactivated by methylation of its 5' CpG islands in epithelial tumor cells, while remaining un-methylated in normal human epithelia. The methylation analy...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-05-01
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Series: | BMC Cancer |
Online Access: | http://www.biomedcentral.com/1471-2407/9/162 |