Nerve injury disrupts temporal processing in the spinal cord dorsal horn through alterations in PV+ interneurons

Summary: How mechanical allodynia following nerve injury is encoded in patterns of neural activity in the spinal cord dorsal horn (DH) remains incompletely understood. We address this in mice using the spared nerve injury model of neuropathic pain and in vivo electrophysiological recordings. Surpris...

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Detalles Bibliográficos
Autores principales: Genelle Rankin, Anda M. Chirila, Alan J. Emanuel, Zihe Zhang, Clifford J. Woolf, Jan Drugowitsch, David D. Ginty
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2024-02-01
Colección:Cell Reports
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Acceso en línea:http://www.sciencedirect.com/science/article/pii/S2211124724000469