Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells

Preclinical evaluation of Affibody molecule for PET imaging of human pancreatic islets derived from stem cells

Abstract Background Beta-cell replacement methods such as transplantation of isolated donor islets have been proposed as a curative treatment of type 1 diabetes, but widespread application is challenging due to shortages of donor tissue and the need for continuous immunosuppressive treatments. Stem-...

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Bibliographic Details
Main Authors: Pierre Cheung, Julia Thorngren, Bo Zhang, Svitlana Vasylovska, Francesco Lechi, Jonas Persson, Stefan Ståhl, John Löfblom, Olle Korsgren, Jonas Eriksson, Joey Lau, Olof Eriksson
Format: Article
Language:English
Published: SpringerOpen 2023-12-01
Series:EJNMMI Research
Subjects:
Affibody molecule
Stem cells
Diabetes
DGCR2
PET
Fluorine-18 chemistry
Online Access:https://doi.org/10.1186/s13550-023-01057-3

Internet

https://doi.org/10.1186/s13550-023-01057-3

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