The Biological Properties of the Strain Francisella tularensis 15 NIIEG with Decreased Gene Expression sodB, Encoding Fe-Dependent Superoxide Dismutase

Relevance. Superoxide anion has bactericidal properties and is also an important inducer of proinflammatory cytokines in macrophages. We have created F. tularensis 15/sodBII strain with transiently decreased FeSOD synthesis level and more sensitive to oxidative stress. So we suggest that the modifie...

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Bibliographic Details
Main Authors: M. A. Sotnikova, T. B. Kravchenko, I. V. Bakhteeva, R. I. Mironova, T. I. Kombarova, A. N. Mokrievich, V. M. Pavlov
Format: Article
Language:Russian
Published: Numikom LLC 2016-10-01
Series:Эпидемиология и вакцинопрофилактика
Subjects:
Online Access:https://www.epidemvac.ru/jour/article/view/354