The Biological Properties of the Strain Francisella tularensis 15 NIIEG with Decreased Gene Expression sodB, Encoding Fe-Dependent Superoxide Dismutase
Relevance. Superoxide anion has bactericidal properties and is also an important inducer of proinflammatory cytokines in macrophages. We have created F. tularensis 15/sodBII strain with transiently decreased FeSOD synthesis level and more sensitive to oxidative stress. So we suggest that the modifie...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | Russian |
Published: |
Numikom LLC
2016-10-01
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Series: | Эпидемиология и вакцинопрофилактика |
Subjects: | |
Online Access: | https://www.epidemvac.ru/jour/article/view/354 |