Circulation of Nor98 Atypical Scrapie in Portuguese Sheep Confirmed by Transmission of Isolates into Transgenic Ovine ARQ-PrP Mice

Circulation of Nor98 Atypical Scrapie in Portuguese Sheep Confirmed by Transmission of Isolates into Transgenic Ovine ARQ-PrP Mice

Portugal was among the first European countries to report cases of Atypical Scrapie (ASc), the dominant form of Transmissible Spongiform Encephalopathy (TSE) in Portuguese small ruminants. Although the diagnostic phenotypes observed in Portuguese ASc cases seem identical to those described for Nor98...

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Bibliographic Details
Main Authors: Mafalda Casanova, Carla Machado, Paula Tavares, João Silva, Christine Fast, Anne Balkema-Buschmann, Martin H. Groschup, Leonor Orge
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
prion
transmissible spongiform encephalopathies
atypical scrapie
transgenic mice
Online Access:https://www.mdpi.com/1422-0067/22/19/10441

Internet

https://www.mdpi.com/1422-0067/22/19/10441

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