Predictive biomarkers for the responsiveness of recurrent glioblastomas to activated killer cell immunotherapy

Predictive biomarkers for the responsiveness of recurrent glioblastomas to activated killer cell immunotherapy

Abstract Background Recurrent glioblastoma multiforme (GBM) is a highly aggressive primary malignant brain tumor that is resistant to existing treatments. Recently, we reported that activated autologous natural killer (NK) cell therapeutics induced a marked increase in survival of some patients with...

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Bibliographic Details
Main Authors: Sohyun Hwang, Jaejoon Lim, Haeyoun Kang, Ju-Yeon Jeong, Je-Gun Joung, Jinhyung Heo, Daun Jung, Kyunggi Cho, Hee Jung An
Format: Article
Language:English
Published: BMC 2023-01-01
Series:Cell & Bioscience
Subjects:
Recurrent GBM
NK therapeutics
Tumor microenvironment
TNFRSF18
TNFSF4
IL12RB2
Online Access:https://doi.org/10.1186/s13578-023-00961-4

Internet

https://doi.org/10.1186/s13578-023-00961-4

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