Retinoic acid receptor agonist as monotherapy for early-stage mycosis fungoides: does it work?

Background: Retinoids exert their biologic effects by binding to intracellular retinoic-acid receptors (RARs) and/or retinoid X receptors (RXRs). Early-stage mycosis fungoides (MF) has been effectively treated with bexarotene, an RXR-agonist, with overall response (OR) rates 54–67% and complete resp...

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Bibliographic Details
Main Authors: Iris Amitay-Laish, Ofer Reiter, Hadas Prag-Naveh, Ruben Kershenovich, Emmilia Hodak
Format: Article
Language:English
Published: Taylor & Francis Group 2019-04-01
Series:Journal of Dermatological Treatment
Subjects:
Online Access:http://dx.doi.org/10.1080/09546634.2018.1487525