Insulin resistance per se drives early and reversible dysbiosis-mediated gut barrier impairment and bactericidal dysfunction

Insulin resistance per se drives early and reversible dysbiosis-mediated gut barrier impairment and bactericidal dysfunction

Objective: A common feature of metabolic diseases is their association with chronic low-grade inflammation. While enhanced gut permeability and systemic bacterial endotoxin translocation have been suggested as key players of this metaflammation, the mechanistic bases underlying these features upon t...

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Bibliographic Details
Main Authors: Dalale Gueddouri, Michèle Caüzac, Véronique Fauveau, Fadila Benhamed, Wafa Charifi, Lucie Beaudoin, Matthieu Rouland, Florian Sicherre, Agnès Lehuen, Catherine Postic, Gaëlle Boudry, Anne-Françoise Burnol, Sandra Guilmeau
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Molecular Metabolism
Subjects:
Insulin resistance
Gut barrier
Dysbiosis
Antimicrobial defenses
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877822000072

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http://www.sciencedirect.com/science/article/pii/S2212877822000072

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