Continuous and Discrete Similarity Coefficient for Identifying Essential Proteins Using Gene Expression Data
Essential proteins play a vital role in biological processes, and the combination of gene expression profiles with Protein-Protein Interaction (PPI) networks can improve the identification of essential proteins. However, gene expression data are prone to significant fluctuations due to noise interfe...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Tsinghua University Press
2023-06-01
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Series: | Big Data Mining and Analytics |
Subjects: | |
Online Access: | https://www.sciopen.com/article/10.26599/BDMA.2022.9020019 |