Continuous and Discrete Similarity Coefficient for Identifying Essential Proteins Using Gene Expression Data

Essential proteins play a vital role in biological processes, and the combination of gene expression profiles with Protein-Protein Interaction (PPI) networks can improve the identification of essential proteins. However, gene expression data are prone to significant fluctuations due to noise interfe...

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Bibliographic Details
Main Authors: Jiancheng Zhong, Zuohang Qu, Ying Zhong, Chao Tang, Yi Pan
Format: Article
Language:English
Published: Tsinghua University Press 2023-06-01
Series:Big Data Mining and Analytics
Subjects:
Online Access:https://www.sciopen.com/article/10.26599/BDMA.2022.9020019