the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin.

the hyphal-associated adhesin and invasin Als3 of Candida albicans mediates iron acquisition from host ferritin.

Iron sequestration by host iron-binding proteins is an important mechanism of resistance to microbial infections. Inside oral epithelial cells, iron is stored within ferritin, and is therefore not usually accessible to pathogenic microbes. We observed that the ferritin concentration within oral epit...

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Bibliographic Details
Main Authors: Ricardo S Almeida, Sascha Brunke, Antje Albrecht, Sascha Thewes, Michael Laue, John E Edwards, Scott G Filler, Bernhard Hube
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-11-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2581891?pdf=render

Internet

http://europepmc.org/articles/PMC2581891?pdf=render

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