The Prc and CtpA proteases modulate cell-surface signaling activity and virulence in Pseudomonas aeruginosa

Summary: Cell-surface signaling (CSS) is a signal transfer system of Gram-negative bacteria that produces the activation of an extracytoplasmic function σ factor (σECF) in the cytosol in response to an extracellular signal. Activation requires the regulated and sequential proteolysis of the σECF-ass...

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Bibliographic Details
Main Authors: Joaquín R. Otero-Asman, Ana Sánchez-Jiménez, Karlijn C. Bastiaansen, Sarah Wettstadt, Cristina Civantos, Alicia García-Puente, Wilbert Bitter, María A. Llamas
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223012932