Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells

Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells

Abstract A poor outcome for cholangiocarcinoma (CCA) patients is still a clinical challenge. CCA is typically recognized by the desmoplastic nature, which accounts for its malignancy. Among various extracellular matrix proteins, laminin is the most potent inducer for CCA migration. Herein, we access...

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Bibliographic Details
Main Authors: Kittiya Islam, Brinda Balasubramanian, Simran Venkatraman, Parichut Thummarati, Janpen Tunganuntarat, Nut Phueakphud, Phongthon Kanjanasirirat, Tanawadee Khumpanied, Pornparn Kongpracha, Yingpinyapat Kittirat, Rutaiwan Tohtong, Tavan Janvilisri, Patompon Wongtrakoongate, Suparerk Borwornpinyo, Nisana Namwat, Tuangporn Suthiphongchai
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-48798-8

Internet

https://doi.org/10.1038/s41598-023-48798-8

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