Perturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in vivo.

Perturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in vivo.

The eye lens presents a unique opportunity to explore roles for specific molecules in cell proliferation, differentiation and development because cells remain in place throughout life and, like red blood cells and keratinocytes, they go through the most extreme differentiation, including removal of...

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Bibliographic Details
Main Authors: Andrea Caceres, Fu Shang, Eric Wawrousek, Qing Liu, Orna Avidan, Ales Cvekl, Ying Yang, Aydin Haririnia, Andrew Storaska, David Fushman, Jer Kuszak, Edward Dudek, Donald Smith, Allen Taylor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2958118?pdf=render

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http://europepmc.org/articles/PMC2958118?pdf=render

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