Induction of lysosomal phospholipase A2 through the retinoid X receptor in THP-1 cells

An acidic phospholipase A2 (LPLA2) was recently purified and cloned. THP-1 cells were used to characterize the gene induction of LPLA2. THP-1 cells were stimulated with several differentiation agents. The LPLA2 mRNA and activity increased in cells treated with phorbol ester but not with vitamin D3,...

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Bibliographic Details
Main Authors: Akira Abe, Heather K. Poucher, Miki Hiraoka, James A. Shayman
Format: Article
Language:English
Published: Elsevier 2004-04-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520318514