GENERATION OF HUMAN MACROPHAGE EXPRESSING CHIMERIC ANTIGEN RECEPTORS DERIVED OF CD34+ CELLS FROM UMBILICAL CORD BLOOD FOR THE TREATMENT OF SOLID TUMORS
Background: T lymphocytes expressing chimeric antigen receptors (CAR) have been shown to be efficient for tretment of hematologic, but less efficient for solid tumors, due to the great complexity of the tumor microenvironment involving: heterogeneity of tumor antigens, difficulty in maintaining and...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-10-01
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| Series: | Hematology, Transfusion and Cell Therapy |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S253113792301951X |