Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer’s disease and Parkinson’s disease: a large-scale multi-trait association analysis

Pinpointing novel risk loci for Lewy body dementia and the shared genetic etiology with Alzheimer’s disease and Parkinson’s disease: a large-scale multi-trait association analysis

Abstract Background The current genome-wide association study (GWAS) of Lewy body dementia (LBD) suffers from low power due to a limited sample size. In addition, the genetic determinants underlying LBD and the shared genetic etiology with Alzheimer’s disease (AD) and Parkinson’s disease (PD) remain...

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Bibliographic Details
Main Authors: Ping Guo, Weiming Gong, Yuanming Li, Lu Liu, Ran Yan, Yanjun Wang, Yanan Zhang, Zhongshang Yuan
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Medicine
Subjects:
Lewy body dementia
Alzheimer’s disease
Parkinson’s disease
Shared genetics
Multi-trait association analysis
Online Access:https://doi.org/10.1186/s12916-022-02404-2

Internet

https://doi.org/10.1186/s12916-022-02404-2

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