Preparation of Oxysterols by C–H Oxidation of Dibromocholestane with Ru(Bpga) Catalyst

Preparation of Oxysterols by C–H Oxidation of Dibromocholestane with Ru(Bpga) Catalyst

Seven mono- and dihydroxycholesterols were prepared by direct C–H oxidation of the cholestane skeleton with a recently developed Ru(Bpga) catalyst (Ru(Bpga) = [RuCl (bpga) (PPh<sub>3</sub>)] Cl; bpga = 2-(bis(pyridin-2-ylmethyl)amino)-<i>N</i>-(2,6-dimethylphenyl)acetamide))....

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Bibliographic Details
Main Authors: Yui Fujii, Makoto Yoritate, Kana Makino, Kazunobu Igawa, Daiki Takeda, Daiki Doiuchi, Katsuhiko Tomooka, Tatsuya Uchida, Go Hirai
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Molecules
Subjects:
cholesterol
oxysterol
C–H oxidation
Ru (bpga)
25-hydroxycholesterol
dihydroxycholesterol
Online Access:https://www.mdpi.com/1420-3049/27/1/225

Internet

https://www.mdpi.com/1420-3049/27/1/225

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