Superagonist CD28 Antibody Preferentially Expanded Foxp3-Expressing nTreg Cells and Prevented Graft-Versus-Host Diseases

Superagonist CD28 Antibody Preferentially Expanded Foxp3-Expressing nTreg Cells and Prevented Graft-Versus-Host Diseases

Regulatory lymphocytes play a pivotal role in preventing organ-specific autoimmune disease and in induction and maintenance of tolerance in various experimental transplantation models. The enhancement of the number and activity of peripheral CD4 + CD25 + Treg cells is an obvious goal for the treatme...

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Bibliographic Details
Main Authors: Yusuke Kitazawa, Masayuki Fujino, Xiao-Kang Li, Lin Xie, Naotsugu Ichimaru, Masayoshi Okumi, Norio Nonomura, Akira Tsujimura, Yoshitaka Isaka, Hiromitsu Kimura, Thomas Hünig, Shiro Takahara
Format: Article
Language:English
Published: SAGE Publishing 2009-05-01
Series:Cell Transplantation
Online Access:https://doi.org/10.1177/096368970901805-619

Internet

https://doi.org/10.1177/096368970901805-619

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