FGF10 ameliorates lipopolysaccharide-induced acute lung injury in mice via the BMP4-autophagy pathway

FGF10 ameliorates lipopolysaccharide-induced acute lung injury in mice via the BMP4-autophagy pathway

Introduction: Damage to alveolar epithelial cells caused by uncontrolled inflammation is considered to be the main pathophysiological change in acute lung injury. FGF10 plays an important role as a fibroblast growth factor in lung development and lung diseases, but its protective effect against acut...

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Bibliographic Details
Main Authors: Xiaoxia Kong, Liling Lu, Daopeng Lin, Lei Chong, Shunhang Wen, Yaokai Shi, Lidan Lin, Liqin Zhou, Hongyu Zhang, Hailin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Pharmacology
Subjects:
acute lung injury
FGF10
BMP4
autophagy
AECs
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.1019755/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.1019755/full

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